Loosely based on the video game of the same name, the film centers on the character of Rayne (Kristanna Loken), an unholy breed of human and vampire called a Dhampir. Dhampir are unaffected by crucifixes and do not thirst for human blood. She is the daughter of the Vampire King Kagan (Ben Kingsley) who has gathered an army of thralls, both vampire and human, in order to annihilate the human race. She was conceived when Kagan raped her mother, and she later witnessed him killing her.Sebastian (Matthew Davis), Vladimir (Michael Madsen), and Katarin (Michelle Rodriguez) are three members of the Brimstone Society, who fight vampires. When they hear of the Dhampir, Vladimir plans to recruit her in order to kill Kagan. A great portion of the story concerns the three body-parts of an ancient vampire that can make a vampire free of the basic weaknesses: holy water (the eye), the cross (the rib), and the sun (the heart). As Kagan wants all these parts, it becomes the heroes' mission to stop him.
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